Canadian minister keeps researchers guessing

Narghile smoking keeps researchers in Wonderland.

After Hours Keeps Clock Researchers CRYing Overtime

Three recent reports, including one in this issue of Cell, reveal that the circadian regulator CRY is targeted for degradation by the F box E3 ubiquitin ligase FBXL3 (Siepka et al., 2007; Busino et al., 2007; Godinho et al., 2007). These studies confirm the importance of targeted protein degradation as a key design feature of the mammalian circadian clock.

Canadian researchers performing world-class research.

I n a typically Canadian way, we (Canadian scientists and physicians) have been quietly performing surgical research in an efficient manner without much fanfare. It has been an ongoing initiative here at the Canadian Journal of Surgery to showcase this research, which is often difficult to have accepted elsewhere. In this issue, we have published unique Canadian perspectives on arthroplasty sur...

Message from the Minister

cause of mental health by creating a greater understanding of the nature of mental disorders and of the possibilities of prevention and of help for those who suffer from them. A lively and well-informed journal is invaluable for stimulating the interest of the public as a whole as well as helping people already actively engaged in work for mental health, and I wish every success to this new ven...

Mad minister disease?

Nearly ten years ago, a hitherto unknown neurological condition, bovine spongiform encephalopathy (BSE), appeared in British cows. It was labelled ‘mad cow disease’, because of the strange combination of fear and shambling gait shown by its victims. As more cases came to light, BSE was found to be similar to scrapie in sheep and it was suggested that cows were infected by eating feedstuffs cont...